{"id":199,"date":"2018-01-29T23:20:16","date_gmt":"2018-01-30T03:20:16","guid":{"rendered":"http:\/\/pilgrimworks.com\/blog\/?p=199"},"modified":"2018-01-29T23:20:16","modified_gmt":"2018-01-30T03:20:16","slug":"eye-surgery","status":"publish","type":"post","link":"https:\/\/pilgrimworks.com\/blog\/?p=199","title":{"rendered":"Eye Surgery"},"content":{"rendered":"<p>On February 1, 2018 I am scheduled to have eye surgery, a procedure known as Descemet\u2019s membrane endothelial keratoplasty (DMEK). Here for the curious is a detailed explanation.<\/p>\n<p>The problem is that the endothelial layer of my cornea is dying. See the detailed diagram below, courtesy of NIH. This thin layer of cells keeps a proper balance of fluids in the cornea; without it the cornea swells, goes cloudy, and eventually forms blisters. The cause is not known but is thought to be partly genetic.<\/p>\n<p><a href=\"http:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/structures_of_the_eye_2.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone wp-image-204 size-full\" src=\"http:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/structures_of_the_eye_2.jpg\" alt=\"structures_of_the_eye_2\" width=\"600\" height=\"674\" srcset=\"https:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/structures_of_the_eye_2.jpg 600w, https:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/structures_of_the_eye_2-267x300.jpg 267w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p>Until about 2000 the only available treatment was\u00a0full-thickness penetrating keratoplasty (PK). This involved removing a large portion of the cornea and replacing it with a donor, sewed in with a dozen stitches and taking a year to heal. Fortunately, this is NOT the procedure I will be having. See the photo below with the visible stitches around the eye.<\/p>\n<p><a href=\"http:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/759px-A_human_eye_1_day_after_a_cornea_transplant.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-medium wp-image-206\" src=\"http:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/759px-A_human_eye_1_day_after_a_cornea_transplant-300x237.jpg\" alt=\"759px-A_human_eye_1_day_after_a_cornea_transplant\" width=\"300\" height=\"237\" srcset=\"https:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/759px-A_human_eye_1_day_after_a_cornea_transplant-300x237.jpg 300w, https:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/759px-A_human_eye_1_day_after_a_cornea_transplant.jpg 759w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>Over the next 15 years doctors learned how to transplant just the inner layers of the cornea through a small incision, resulting in much quicker healing and much better vision. They have gradually decreased the thickness of the transplant until now DMEK, the procedure I will have, transplants only the inner two layers, about\u00a0 10 microns thick (illustration C in the drawing below).<\/p>\n<p><a href=\"http:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/PMC2880365_MEAJO-17-05-g001.png\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone wp-image-205 size-full\" src=\"http:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/PMC2880365_MEAJO-17-05-g001.png\" alt=\"PMC2880365_MEAJO-17-05-g001\" width=\"512\" height=\"494\" srcset=\"https:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/PMC2880365_MEAJO-17-05-g001.png 512w, https:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/PMC2880365_MEAJO-17-05-g001-300x289.png 300w\" sizes=\"(max-width: 512px) 100vw, 512px\" \/><\/a><\/p>\n<p>The procedure is out-patient and takes less than an hour. To keep the graft sticking to the cornea they inject a gas bubble to hold it in place.<\/p>\n<p><a href=\"http:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/8A-LRG-sp-DMEK-for-Fuchs.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-medium wp-image-207\" src=\"http:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/8A-LRG-sp-DMEK-for-Fuchs-300x200.jpg\" alt=\"8A-LRG-sp-DMEK-for-Fuchs\" width=\"300\" height=\"200\" srcset=\"https:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/8A-LRG-sp-DMEK-for-Fuchs-300x200.jpg 300w, https:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/8A-LRG-sp-DMEK-for-Fuchs-1024x683.jpg 1024w, https:\/\/pilgrimworks.com\/blog\/wp-content\/uploads\/2018\/01\/8A-LRG-sp-DMEK-for-Fuchs.jpg 2048w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>Donaghy CL, Vislisel JM, Greiner MA. An Introduction to Corneal Transplantation. May 21, 2015; Available from: http:\/\/EyeRounds.org\/tutorials\/cornea-transplant-intro\/<\/p>\n<p>To keep the bubble from floating to the top of the eye (as in the photo above), I need to lie flat on my back for a day, maybe two or three. As the bubble goes away, if the graft takes hold and starts working, my vision will quickly return to normal. I hope to return to school one week later. Within just a few weeks many patients are back to 20\/20 vision.<\/p>\n<p>This is a transplant of tissue from an donor eye (a big thank you to some anonymous organ donor), so there is a risk of rejection. For this reason I will take daily steroid eye drops indefinitely. That is a small price for good vision.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>On February 1, 2018 I am scheduled to have eye surgery, a procedure known as Descemet\u2019s membrane endothelial keratoplasty (DMEK). Here for the curious is a detailed explanation. The problem is that the endothelial layer of my cornea is dying. &hellip; <a href=\"https:\/\/pilgrimworks.com\/blog\/?p=199\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[14,3],"tags":[16,15],"_links":{"self":[{"href":"https:\/\/pilgrimworks.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/199"}],"collection":[{"href":"https:\/\/pilgrimworks.com\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pilgrimworks.com\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pilgrimworks.com\/blog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pilgrimworks.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=199"}],"version-history":[{"count":2,"href":"https:\/\/pilgrimworks.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/199\/revisions"}],"predecessor-version":[{"id":208,"href":"https:\/\/pilgrimworks.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/199\/revisions\/208"}],"wp:attachment":[{"href":"https:\/\/pilgrimworks.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=199"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pilgrimworks.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=199"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pilgrimworks.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=199"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}